Jim Simons acquired 2 Million Abbvie shares worth $328 Million. That's 0.50% of their equity portfolio (25th largest holding). The first Abbvie trade was made in Q2 2013. Since then Jim Simons bought shares 21 more times and sold shares on 21 occasions. The stake costed the investor $183 Million, netting the investor a gain of 79% so far.